啤酒花中异葎草酮体外抗肿瘤作用及机制研究

研究啤酒花(Humulus Lupulus L.)中成分异葎草酮(tetrahydro-iso-α-acid)对人胃腺癌细胞SGC-7901和人肝癌细胞HepG-2的体外抑制作用,并初步揭示其抗肿瘤的作用机制.以MTT法进行细胞毒测定;采用流式细胞仪观察异葎草酮对肿瘤细胞凋亡的影响;细胞线粒体跨膜电位(MMP)测定用罗丹明123(Rhodamine l23,Rh123)标记,以流式细胞仪检测.异葎草酮对SGC-7901和HepG-2的IC50分别为13.4μg/mL和11.58μg/mL.异葎草酮作用于SGC-7901和HepG-2细胞48 h后,肿瘤细胞均有明显凋亡峰出现.异葎草酮可以导致SGC-7901和HepG-2细胞内线粒体膜电位明显下降,并呈剂量依赖关系.结果表明,异葎草酮对肿瘤细胞SGC-7901及HepG-2均有较强抑制作用,这一作用是通过诱导肿瘤细胞凋亡实现的.异葎草酮是通过线粒体路径启动细胞凋亡的,而且诱导线粒体功能异常可能是其引起细胞凋亡发生的主要作用机理.     

用D2EHPA从硫酸介质中萃取锌

以低品位硫化矿的资源综合利用为背景,研究了D2EHPA和D2EHPATOA两个不同体系萃锌的适宜条件.实验结果表明, D2EHPATOA协萃体系在萃取与反萃取的难易程度以及经济效益等方面均优于单独D2EHPA体系.在此基础上,提出了从细菌浸出液中回收锌的工艺.     

维特根斯坦对现代科学文化的反思

站在古典文化立场上批判现代科学文化，一直是维特根斯坦思想的主要导向。维特根斯坦认为古人和现代人有着不同的语言和生活世界（做着不同的语言游戏），因此不能用现代科学的观念去批判或否定古人。反而是现代科学因其过度膨胀到统治一切的地步，使人类远离了崇高的精神，因此，维特根斯坦呼唤一种新的文化和生活方式的诞生。     

Atomic-beam alignment of inorganic materials for liquid-crystal displays

The technique used to align liquid crystals-rubbing the surface of a substrate on which a liquid crystal is subsequently deposited-has been perfected by the multibillion-dollar liquid-crystal display industry. However, it is widely recognized that a non-contact alignment technique would be highly desirable for future generations of large, high-resolution liquid-crystal displays. A number of alternative alignment techniques have been reported, but none of these have so far been implemented in large-scale manufacturing. Here, we report a non-contact alignment process, which uses low-energy ion beams impinging at a glancing angle on amorphous inorganic films, such as diamond-like carbon. Using this approach, we have produced both laptop and desktop displays in pilot-line manufacturing, and found that displays of higher quality and reliability could be made at a lower cost than the rubbing technique. The mechanism of alignment is explained by adopting a random network model of atomic arrangement in the inorganic films. Order is induced by exposure to an ion beam because unfavourably oriented rings of atoms are selectively destroyed. The planes of the remaining rings are predominantly parallel to the direction of the ion beam.     

Imaging the effects of individual zinc impurity atoms on superconductivity in Bi2Sr2CaCu2O8+delta

Although the crystal structures of the copper oxide high-temperature superconductors are complex and diverse, they all contain some crystal planes consisting of only copper and oxygen atoms in a square lattice: superconductivity is believed to originate from strongly interacting electrons in these CuO2 planes. Substituting a single impurity atom for a copper atom strongly perturbs the surrounding electronic environment and can therefore be used to probe high-temperature superconductivity at the atomic scale. This has provided the motivation for several experimental and theoretical studies. Scanning tunnelling microscopy (STM) is an ideal technique for the study of such effects at the atomic scale, as it has been used very successfully to probe individual impurity atoms in several other systems. Here we use STM to investigate the effects of individual zinc impurity atoms in the high-temperature superconductor Bi2Sr2CaCu2O8+delta. We find intense quasiparticle scattering resonances at the Zn sites, coincident with strong suppression of superconductivity within approximately 15 A of the scattering sites. Imaging of the spatial dependence of the quasiparticle density of states in the vicinity of the impurity atoms reveals the long-sought four-fold symmetric quasiparticle 'cloud' aligned with the nodes of the d-wave superconducting gap which is believed to characterize superconductivity in these materials.     

江西庐山自然保护区药用植物资源

据江西庐山自然保护区药用植物调查显示,该保护区共有1 859种药用植物,其中药用藻类4种,药用真菌22种,药用地衣10种,药用苔藓21种,药用蕨类131种,药用种子植物1611,常用中药328种,药用珍稀濒危植物137种,药用观赏植物180余种,药用特有种植物116种,农兽药植物169种。此外,还发现24种江西地区记录新分布,模式标本24种,以庐山、牯岭命名的植物有25种,并介绍了药用植物资源合理利用的概况。     

论编辑能力对学报质量的影响

文章对编辑工作能力与学报质量的关系作了一些探讨。认为编辑在实际工作中所表现出来的能力,不仅体现个人在工作中的实际水平,而且体现出编辑部综合实力的大小,某个编辑环节出了问题,就会直接影响到学报的质量。     

山西省各城市投资环境综合评估研究

介绍了城市投资环境指标体系的构建思路,运用主成分分析方法对山西省各城市投资环境进行了综合评估,以此提高山西省投资环境.     

领会创新思路激发创新活力

党的十七大高举中国特色社会主义伟大旗帜,充分肯定我国依靠自主创新所取得的重大成绩,同时为科技型企业的发展明确了方向。走中国特色自主创新道路,必须切实领会党中央的创新思路,激发创新活力。企业应积极开展产业集群技术联盟工作,围绕集群企业的共性科技需求,整合科技资源,共建创新平台,降低研发成本,扩大生产规模,提高科技创新效率和自主创新能力。     

西藏芒康县盐井化探异常分布规律及找矿标志

盐井属于藏东昌都地区芒康县,地处于著名的三江成矿区;藏东地质构造复杂,成矿条件优越,具备形成铜、金、铅、锌、银矿的地质背景,是中国重要的多金属成矿带。根据1∶20万区域化探异常特征优选了芒康县盐井开展1∶5万地球化学测量,Au、Cu、Ag、Pb元素套叠好,异常强度大,属于典型的矿致异常,找矿前景十分广阔,是该区重要找矿靶区。